| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4006211 | American Journal of Ophthalmology | 2007 | 8 Pages |
Abstract
A large family with autosomal dominant inheritance of cavitary ONH anomalies and abnormal vasculature is presented. Clinical phenotypes varied markedly. Progressive ONH cupping was documented in four eyes of two patients. Genetic linkage analysis of this family has identified the chromosomal location of a gene responsible for ONH development. This may provide insight into the pathogenesis of glaucomatous ONH damage.
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Authors
Robert A. Honkanen, Lee M. Jampol, John H. Fingert, Michael D. Moore, Christine M. Taylor, Edwin M. Stone, Wallace L.M. Alward,