Article ID Journal Published Year Pages File Type
4015365 Journal of American Association for Pediatric Ophthalmology and Strabismus 2008 5 Pages PDF
Abstract

PurposeTo assess the normative data of the retinal nerve fiber layer (RNFL) thickness in healthy children using the scanning laser polarimeter with variable corneal compensation (GDxVCC).MethodsOf the 186 enrolled white school-aged children, 120 subjects of the mean 12.85 ± 3.0 years (age ± SD) fulfilled inclusion criteria. After complete ophthalmic examination, including GDxVCC, 240 normal eyes were analyzed. Evaluation of RNFL thickness in GDxVCC temporal-superior-nasal-inferior-temporal (TSNIT) parameters was performed, and probability of normality was calculated. The influence of sex and age was investigated.ResultsThe mean ± SD values in TSNIT Average, Superior Average, Inferior Average, and TSNIT SD were 58.98 ± 6.92 μm, 72.99 ± 8.97 μm, 71.18 ± 10.92 μm, and 26.30 ± 4.92 μm. The values of 5% probability of normality in the same order were 47.6 μm, 58.2 μm, 53.2 μm, and 18.2 μm. The mean values of Inferior Average and TSNIT SD were greater in left eyes by 1.84 ± 6.6 μm (p = 0.003) and by 3.04 ± 3.8 μm (p < 0.00005), respectively. No correlation to sex and age was found.ConclusionsRNFL thickness assessed using GDxVCC was greater in children compared with previous published data in healthy adults. The values of Inferior Average and TSNIT SD were significantly greater in left eyes.

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