Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4022275 | Journal of Cataract & Refractive Surgery | 2006 | 7 Pages |
Abstract
Results suggest that epithelial healing after MMC is characterized by prolonged latency and decreased migration rate dependent on exposure time. Mitomycin C application did not result in increased loss of keratocytes, but it significantly delayed keratocyte repopulation in the anterior stroma. The use of MMC 0.2 μg/mL for 1 minute resulted in optimum modulation of healing characterized by reduced keratocyte activation with normal epithelial differentiation.
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Authors
Madhavan S. MRCOphth, FRCS, David P.S. MD, FRCS, FRCOphth, Anne Patmore, John PhD,