Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4024644 | Journal Français d'Ophtalmologie | 2009 | 5 Pages |
Abstract
The clinical diagnosis of ocular toxoplasmosis is based on clinical features and biological tests: polymerase chain reaction (PCR) and the determination of intraocular specific antibody secretion (Goldmann-Witmer coefficient) on aqueous humor. Older patients may have a higher prevalence of ocular involvement and more severe ocular disease during the acute phase of recently acquired systemic infection because of altered cell-mediated immunity. Moreover, the genotype of the infecting parasite (particularly involving neotropical Type I Toxoplasma gondii strain), appears to be an important determinant of disease severity.
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Authors
M.H. Errera, S. Chahed, H. Man, Y.J.F. Garin, J.F. Bergmann, A. Gaudric, P. Massin,