| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4025803 | Ophthalmology | 2015 | 11 Pages |
Abstract
Persistent and dynamic, the onion sign represents sub-RPE cholesterol crystal precipitation in an aqueous environment. The frequency of the onion sign in neovascular AMD in a referral practice and a pathology archive is 5% to 7%. Associations include use of cholesterol-lowering medication and intraretinal hyperreflective foci attributable to RPE cells and lipid-filled cells of monocyte origin.
Keywords
NIRAMDRPEPEDsloScanning laser ophthalmoscopyNear-infrared reflectanceretinal pigment epitheliumOctOptical coherence tomographyPigment epithelial detachmentspectral-domainage-related macular degenerationVascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)esterified cholesterolunesterified cholesterolBlind
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Authors
Claudine E. MD, Jeffrey D. DC, Emma C. MD, K. Bailey MD, Christine A. PhD,