Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4026170 | Ophthalmology | 2014 | 10 Pages |
Abstract
Pseudoxanthoma elasticum-like fundus changes are a frequent finding in patients with β-thalassemia. In TI, these changes increase with duration or severity of the disease. This particular ocular phenotype suggests an ocular pathology similar to PXE. Retinal vascular tortuosity may be an additional disease manifestation independent of the PXE-like syndrome. Patients with long-standing disease requiring iron-chelating treatment and a history of splenectomy need regular ophthalmic checkups because they are at risk of developing PXE-like fundus changes and potentially of subsequent choroidal neovascularization.
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Authors
Giulio MD, Laura MD, Robert P. MD, Peter MD, Alessia MD, Diego MD, Chiara MD, Elena MD, Maria D. MD, Roberto MD, Francesco MD,