Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4032520 | Survey of Ophthalmology | 2015 | 12 Pages |
Abstract
Corneal lymphangiogenesis is the extension of lymphatic vessels into the normally alymphatic cornea, a process that compromises the cornea's immune-privileged state and facilitates herpetic stromal keratitis (HSK). HSK results most commonly from infection by herpes simplex virus-1 (HSV-1) and is characterized by immune- and inflammation-mediated damage to the deep layers of the cornea. Current research demonstrates the potential of anti-lymphangiogenic therapy to decrease and prevent herpes-induced lymphangiogenesis.
Keywords
Related Topics
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Medicine and Dentistry
Ophthalmology
Authors
Paul J. Park, Michael Chang, Nitin Garg, Jimmy Zhu, Jin-Hong Chang, Deepak Shukla,