| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4033217 | Survey of Ophthalmology | 2007 | 10 Pages |
Abstract
A 64-year-old woman presented with bilateral optic nerve swelling, vitreous cells, and cerebrospinal fluid monocytic pleocytosis. A chest radiograph and computed tomography demonstrated a lesion in the left lung, which histologically was confirmed to be a small-cell lung carcinoma. The serum was positive for the anti-CV2 (anti-CRMP-5) antibody. Following treatment with chemoradiation the optic nerve swelling and vitritis resolved. The differential diagnosis of uveal-meningeal diseases is discussed and the pathophysiology and clinical manifestations of paraneoplastic syndromes reviewed.
Keywords
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Authors
M. Tariq Bhatti, Katherine E. Gres, Virginia B. Petitto, Shelley Ann Cross,