Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4035047 | Vision Research | 2008 | 9 Pages |
Abstract
The most widespread models to study blindness, rats and mice, have retinas containing less than 3% cones. The diurnal rodent Arvicanthis niloticus retina has around 35% cones. Using ERG recordings, we studied retina function in this species. Several features differed from that reported in rats and mice: (a) fivefold larger photopic a-wave amplitudes; (b) photopic hill effect in Nile grass rats only; and (c) flicker amplitude plateau between 5 to 35 Hz with fusion beyond 60 Hz in Nile grass rats only. We conclude that A. niloticus might complement rats and mice for studying retinal function and pathologies involving cones.
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Authors
Gregory S. Gilmour, Frédéric Gaillard, Juliane Watson, Sharee Kuny, Silvina C. Mema, Stephan Bonfield, William K. Stell, Yves Sauvé,