Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4035090 | Vision Research | 2008 | 8 Pages |
Abstract
We used optical imaging of intrinsic signals to study visual cortex responses in three mouse strains: wild-type (C57BL/6J), a strain with only rod function (cpfl1), and a strain with only cone function (rho−/−). A stationary flicker light stimulus with intensity ranging from 108.6 to 1015.5 photons/cm2/s was used. We found that the intrinsic signal patterns exhibited stimulus intensity-dependent changes. At a given stimulus intensity, the patterns of intrinsic signals were clearly different in the three strains. These results suggest that the lack of normal functions of certain photoreceptors induces significant reorganization in the visual neural systems in mice.
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Authors
Xiaofei Fan, Bo Lei, Keqing Zhang, Gang Yao,