| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4035229 | Vision Research | 2008 | 8 Pages |
Abstract
Focal macular cone electroretinograms (ERGs) and multifocal ERGs were recorded to study the macular function in patients with the complete-type of congenital stationary night blindness (cCSNB). The waveforms of the focal macular cone ERGs and the on- and off-responses of the multifocal ERGs in the cCSNB patients were similar to those recorded from monkey retinas treated with L-2 amino-4-phosphonobutyric acid (APB), suggesting that patients with cCSNB have a complete defect of the on-pathway even in the central retina. The results also demonstrated that there was a paradoxical positive response in the central retina of cCSNB patients, as compared to the negative full-field ERGs in the same subjects.
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Authors
Mineo Kondo, Shinji Ueno, Chang-Hua Piao, Yozo Miyake, Hiroko Terasaki,