Flicker VEPs reflecting multiple rod and cone pathways

In an attempt to determine whether the relative contributions of magno-mediated and parvo-mediated inputs to the cortex are significantly altered in the transition from cone to rod vision, VEPs were recorded at different luminance levels (photopic to scotopic) for 2 Hz square-wave, isochromatic flicker. The VEP mass response appears capable of reflecting major parvo-mediated contributions even at luminance levels for which responses from individual cells in the parvocellular pathway are reported to be weak. Our findings suggest that parvo-mediated responses are the dominant source of high-contrast isochromatic flicker VEPs at all light levels.