Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4036745 | Vision Research | 2006 | 10 Pages |
Abstract
The purpose of this study was to compare the a-waves of mGluR6-deficient mice (KO) to that of wild-type mice (WT), and to determine whether the light-adapted electroretinogram of the KO mice originate exclusively from cones. Dark-adapted a-waves were recorded under the same conditions from both types of mice. With a 96-cd/m2 background, the a-wave from both types of mice showed a rapid recovery over a 50-min period. The analysis of the a-waves in KO mice indicated that the recovery was determined mainly by the rod component. The light-adapted b-wave of WT mice showed no corresponding recovery. We conclude that rod contribution must be considered in the analyses of the light-adapted a-waves of KO mice.
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Authors
Yoshiki Ueda, Noritomo Tammitsu, Hiroo Imai, Yoshihito Honda, Yoshinori Shichida,