Phospha-Michael addition of diethyl phosphite to α,β-unsaturated malonates catalyzed by nano γ-Fe2O3-pyridine based catalyst as a new magnetically recyclable heterogeneous organic base

Nano γ-Fe2O3-pyridine based catalyst as a new magnetically recyclable heterogeneous organic base was synthesized. The synthesized odorless pyridine based catalyst was used as a new catalyst for the efficient synthesis of β-phosphonomalonates by the reaction of diethyl phosphite with α,β-unsaturated malonates. The catalyst was easily isolated from the reaction mixture by a magnetic bar and reused at least 10 times without significant degradation in the activity.

Graphical abstractFigure optionsDownload full-size imageDownload high-quality image (122 K)Download as PowerPoint slideHighlights► A pyridine based catalyst supported on γ-Fe2O3 nanoparticles was synthesized. ► It was used as a recyclable catalyst for the synthesis of β-phosphonomalonates. ► β-phosphonomalonates were obtained in good to high yields. ► In this method, catalyst separation was easily performable by a magnetic bar.