| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4072426 | Journal of Orthopaedic Science | 2008 | 6 Pages |
Abstract
Simvastatin and pravastatin significantly reduced the incidence of steroid-induced osteonecrosis in rabbits. Simvastatin was more effective in reducing the incidence of the disease, and increased CYP3A activity is a possible mechanism for this effect.
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Authors
Kentaro Iwakiri, Yutaka Oda, Yasunori Kaneshiro, Hiroyoshi Iwaki, Toshiaki Masada, Akio Kobayashi, Akira Asada, Kunio Takaoka,