| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4072481 | Journal of Orthopaedic Science | 2009 | 6 Pages |
Abstract
10-6 M Raloxifene had no ossification-inducing effect on female MSCs, but it had an ossification-promoting effect; it had no osteogenic effect on male MSCs. Therefore, raloxifene has a sex difference with regard to its osteogenic effect on MSCs. Moreover, combined treatment with raloxifene plus OS has an effect on female MSCs. These results provide a useful insight into the possible influence of raloxifene after MSC transplantation in clinical practice.
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Authors
Hiroaki Matsumori, Koji Hattori, Hajime Ohgushi, Yoshiko Dohi, Yurito Ueda, Hideki Shigematsu, Nobuhisa Satoh, Hiroshi Yajima, Yoshinori Takakura,