Article ID Journal Published Year Pages File Type
4080442 Orthopaedics and Trauma 2010 11 Pages PDF
Abstract

Osteosarcomas are rare malignant tumours that produce osteoid. The investigation, diagnosis, treatment and follow-up of these rare tumours should be directed by multi-disciplinary teams in centralized, specialist centres. Here, we discuss the epidemiology, investigation and management of these tumours, and explore the literature on limb-salvage and adjuvant therapy. Local and systemic recurrences are discussed and the evidence base regarding prognosis is reviewed.

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