Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4094927 | Seminars in Spine Surgery | 2009 | 4 Pages |
Abstract
Spine care has become increasingly evidence-based. The investigators who have generated this evidence have learned important lessons that should help guide future trials: 1. Patients will agree to enroll in studies and to be randomized; 2. Patients will crossover between treatment arms if it is an option; 3. Observational studies can provide the best answers to some questions; 4. High quality clinical research is extremely expensive and work-intensive; 5. High quality spine research is needed now more than ever. This paper reviews these issues as they have arisen in recent clinical studies.
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Authors
Adam M. MD, MS, James N. DO, MS,