Gorham disease of the craniocervical junction: X-ray, computed tomography, and magnetic resonance imaging findings

Background contextGorham disease of massive osteolysis is a spontaneous, idiopathic, and progressive form of primary osteolysis. It has no age, sex, or race predilection, and patients are mostly asymptomatic until severe deformity or pathological fracture becomes evident.PurposeA patient with craniocervical involvement is presented, describing imaging findings with a review of the literature to provide an insight into the disorder.Study design/settingCase report and review of the literature.MethodsX-ray, computed tomography, and magnetic resonance imaging findings of a patient with findings related to the site of involvement.ResultsAll images demonstrate osteolysis typically described for the disease. Differential diagnosis and key features are indicated. Operative findings and pathological analysis were also consistent with the findings. Patient's follow-up is also reported.ConclusionsThis benign appearing yet disabling disease may become fatal in relation to the site involved. Acknowledging imaging findings may provide early diagnosis for timely intervention or supportive management.