| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4110455 | European Annals of Otorhinolaryngology, Head and Neck Diseases | 2010 | 4 Pages |
SummaryObjectivesTo assess the incidence and impact on treatment and prognosis of occult lymph node metastasis in laryngeal cancer.Patients and methodsA retrospective study was performed on 164 patients treated for laryngeal cancer, initially classified as N0, with cervical lymph node dissection.ResultsOccult metastases were found in 41 neck specimens (12.5%) from 32 patients (19.5%). Involvement per neck level was: 7% level IIa, 2.4% IIb, 4.2% III and 2.7% IV. Lymph node involvement was significantly increased in case of T3T4 tumor or invasion of the pre-epiglottic space or cartilage. Survival was significantly influenced by pN status (pN- = 12 years, vs pN+ = 9 years; P = 0.006).ConclusionLevel IIb or IV involvement is rare. Superselective neck dissection (IIa, III) seems to be indicated in T1T2 N0 tumor. In case of advanced tumor or pre-epiglottic space or cartilage invasion, functional neck dissection is mandatory.
