Article ID Journal Published Year Pages File Type
4115164 International Journal of Pediatric Otorhinolaryngology 2009 4 Pages PDF
Abstract

ObjectiveTo review the current evidence for the use of concomitant interventions to reduce the persistent perforation rate following the removal of long-term ventilation tubes.Type of reviewA systematic review of the literature and meta-analysis of randomised controlled trials on this topic.Search strategyMedline (1952–2008), EMBASE (1974–2008) and the Cochrane Central Register of Controlled Trials. A combination of search terms were used in a search strategy derived from guidance from the Cochrane collaboration.Evaluation methodA review of all trials by two authors with grading of the level of evidence.ResultsFifteen studies using a variety of interventions were identified.ConclusionA multi-centre randomised controlled trial is indicated to validate findings of previous studies and elucidate any optimum intervention to reduce the persistent perforation rate.

Related Topics
Health Sciences Medicine and Dentistry Otorhinolaryngology and Facial Plastic Surgery
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