Subglottic diffuse large B-cell lymphoma presenting as biphasic stridor

The management of airway obstruction in children is often challenging with acute presentation and uncertainty in the diagnosis. We report a case of a young child with acute onset biphasic stridor who was found to have a large subglottic lesion causing significant airway obstruction. We were able to successfully resect it to achieve a pathologic diagnosis and address the subglottic stenosis with an anterior laryngofissure followed by laryngotracheal reconstruction (LTR) using a rib graft. The final pathology was diffuse large B-cell lymphoma, anaplastic variant, and patient had complete response to chemotherapy and is currently free of disease.