Adenomatoid odontogenic tumor arising from a dentigerous cyst—A case report

SummaryAdenomatoid odontogenic tumor (AOT) is a benign lesion derived from the complex system of dental lamina or its remnant. It is categorized into three variants (follicular, extrafollicular and peripheral). To our knowledge, there are only six existing cases of AOT associated with dentigerous cyst. We present an additional case from a dentigerous cyst around the crown of an unerupted canine in a 15-year-old boy. We provide histological evidence of an ‘odontoma-like’ area, as has been described in only one other previous case report. The clinical characteristics of our patient and the six previously reported cases are also briefly discussed. We believe that this case represents an odontogenic cyst with neoplastic development, containing both epithelial and mesenchymal components. As more cases accumulate, we will be able to study these rare lesions further whether the AOTs derived from an odontogenic cyst could represent a distinct ‘hybrid’ variant (separate to the three variants described thus far).