Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4121744 | Journal of Plastic, Reconstructive & Aesthetic Surgery | 2009 | 7 Pages |
Abstract
G-CSF promotes angiogenesis by increasing the number of activated and proliferating endothelial cells within the ischaemic flaps by the resettlement of G-CSF-stimulated endothelial progenitor cells into the ischaemic tissue. The overall result is an improved survival of ischaemic skin flaps. These effects are more pronounced when G-CSF is introduced 2 days prior to flap elevation.
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Authors
Alper Sari, Onur Gurbuz, Necat Yilmaz, Gulcin Eskandari, Bahar Tasdelen, Yavuz Basterzi,