Article ID Journal Published Year Pages File Type
4124842 Otolaryngology - Head and Neck Surgery 2010 25 Pages PDF
Abstract
This pilot study examined the contribution of global DNA hypermethylation to the pathogenesis of HNSCC. The whole-genome methylation approach indicated 231 new genes with methylated promoter regions not yet reported in HNSCC. Examination of this comprehensive gene panel in a larger HNSCC cohort should advance selection of HNSCC-specific candidate genes for further validation as biomarkers in HNSCC.
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Health Sciences Medicine and Dentistry Otorhinolaryngology and Facial Plastic Surgery
Preview
Novel approaches to global mining of aberrantly methylated promoter sites in squamous head and neck cancer
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