| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4125166 | Otolaryngology - Head and Neck Surgery | 2010 | 7 Pages |
Abstract
Our recent investigations indicate that inflammatory mediators are potent regulators of EMT in HNSCC. This is the first report indicating the role of ZEB1 in the inflammation-induced promotion of EMT in HNSCC. This newly defined pathway for transcriptional regulation of E-cadherin in HNSCC has important implications for targeted chemoprevention and therapy.
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Authors
Mariam PhD, Guanyu MD, PhD, Eileen MS, Jie Luo, Ontario MD, Hubert MD, Qahera Munaim, Gina MD, Longsheng MS, Chi MD, Elliot MD, Michael C. MD, David A. PhD, Steven M. MD, Maie A. MD, PhD,