Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4128074 | Annales de Pathologie | 2015 | 5 Pages |
Abstract
Basal cell carcinoma with matrical differentiation is a very rare variant of basal cell carcinoma. To our knowledge, less than 30 cases have been reported. This tumor is composed of basaloid lobules showing a differentiation toward the pilar matrix cells. Recently, it has been demonstrated that beta-catenin would interfer with physiopathogenesis of matrical tumors, in particular pilomatricomas, but also basal cell carcinomas with matrical differentiation. This is a new case, with immunohistochemical and molecular analysis of beta-catenin, in order to explain its histogenesis.
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Authors
Gabrielle Goldman-Lévy, Eric Frouin, Isabelle Soubeyran, Géraldine Maury, Bernard Guillot, Valérie Costes,