Maladie de Paget vulvaire micro-invasive et métastase ganglionnaire : une même maladie ?

Vulvar Paget's disease is sub-classified into three types based upon its origin. It might be a primary vulvar disease (type 1) or associated with a non-cutaneous adenocarcinoma-rectal, colonic, cervical (type 2) or linked with an urothelial neoplasia (type 3). Type 1 lesions must be considered as potentially invasive. Their immunophenotype is CK7+ / CK20-. Classically, in case of depth of invasion below 1 mm, nodal metastases are exceptional. We report a case of type 1 Paget's disease in a postmenopausal woman with superficial invasion and multiple inguinal nodal metastases.