Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4128897 | Annales de Pathologie | 2008 | 4 Pages |
Abstract
Persistent subcutaneous nodules arise on rare occasions at sites of injection of aluminium hydroxide-adsorbed vaccine. We report a case following a diphtheria, tetanus and pertussis vaccination. The late onset of the lesion, four years after the injection, led to an uncertain preoperative diagnosis. Histopathologic examination showed features of a subcutaneous pseudolymphoma. The demonstration of aluminium by Morin staining and atomic absorption spectrometry on a paraffin-embedded tissue probe supported the diagnosis of a vaccination-induced pseudolymphoma.
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Authors
Sabrina Croce, Benoît Lhermitte, Catherine Tomasetto, Olivier Guillard, Jean-Pierre Bellocq, Marie-Pierre Chenard,