Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4128981 | Annales de Pathologie | 2008 | 5 Pages |
Abstract
Hematogones are bone marrow precursors of B-lymphoid cells which are morphologically difficult to distinguish from blasts and/or from small lymphocytes. We report the case of a patient presenting idiopathic myelofibrosis with minimal myeloid blastic transformation causing severe pancytopenia, treated by allograft and showing in a bone marrow biopsy, a hyperplasia of B-lymphoid cells. Histopathology and immunohistochemistry identified these cells as hyperplasia of hematogones and not a transformation into lymphoblastic acute leukaemia. The cytology of a myelogram confirmed the diagnosis.
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Authors
Bienvenu Massamba Lebwaze, Agnès Le Tourneau, Bernard Rio, Jean-Yves Perrot, Laurence Heuberger, Jean-Marie Mpolesha Kabongo, Raphaël Mbowa Kalengayi, Thierry Molina, Jacques Diebold, Josée Audouin,