Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4130226 | Annals of Diagnostic Pathology | 2009 | 4 Pages |
Abstract
A case of exceptionally rare odontogenic malignant tumor, called ghost cell odontogenic carcinoma, is described. The tumor was considered to be derived from calcifying odontogenic cyst, which had been resected 5 years before. In the present resected specimen, cellular atypia, mitotic activity, Ki-67 labeling index, and p53 positivity were all increased in comparison with the initially resected specimen. This is a valuable case in which malignant transformation from calcifying odontogenic cyst to ghost cell odontogenic carcinoma was proven by the histopathologic and immunohistochemical findings. Pathologists should be aware of this rare entity.
Keywords
Related Topics
Health Sciences
Medicine and Dentistry
Pathology and Medical Technology
Authors
Utaroh Motosugi, Ikuko Ogawa, Tetsuya Yoda, Takahiro Abe, Masashi Sugasawa, Shin-ichi Murata, Masanori Yasuda, Takaki Sakurai, Yoshihiko Shimizu, Michio Shimizu,