Handling and reporting of radical prostatectomy specimens

An accurate reporting of radical prostatectomy specimens is becoming more important as we gain insights in how cancer therapy should be taylored according to risk stratification. The handling of these specimens must therefore be standardized and enable the correct identification of histopathological risk factors for poor outcome. Several efforts have been made in recent years to reach consensus on the handling and reporting of radical prostatectomy specimens. Some of the recommendations are summarized in this review, including guidelines for gross description, fixation, cutting and reporting of stage and grade related data. Methods for biobanking of fresh tissue are also described.