The impact of advances in molecular genetics on the classification and diagnosis of liposarcoma

Advances in our understanding of the genetic underpinnings of human neoplasia have revolutionized the classification and diagnosis of tumours. This impact has been particularly profound in the field of sarcoma pathology. This article will summarize our current knowledge of the cytogenetic and molecular genetic basis of liposarcomas specifically, and will review the impact of advances in these fields on the classification and diagnosis of these tumours.