Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4134727 | Human Pathology | 2008 | 4 Pages |
Abstract
SummaryMucinous tubular and spindle cell carcinoma (MTSCC) is a recently described renal epithelial tumor. The bland cytomorphology of the spindled component and low-grade behavior help in its differentiation from sarcomatoid renal carcinoma. Sarcomatoid change has been reported in most histologic variants of renal cell carcinoma apart from MTSCC. Herein we report a case of an MTSCC in a 72-year-old female patient with high-grade spindled areas resembling fibrosarcomatous and undifferentiated pleomorphic sarcoma patterns with metaplastic bone. This index case also demonstrates a high proliferation index and extensive necrosis representing the first documented case of sarcomatoid change in MTSCC.
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Authors
Nischalan Pillay, Pratistadevi K. Ramdial, Kumarasen Cooper, David Batuule,