Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4135215 | Human Pathology | 2006 | 6 Pages |
Abstract
SummaryThe very recent discovery of B-RAF point mutations as the most prevalent genetic alteration in papillary thyroid carcinoma has revolutionized the molecular knowledge of thyroid malignancies. In this review, we address the role played by such mutations in the etiopathogenesis, diagnosis, prognosis, and therapy selection of thyroid cancer, with an emphasis on papillary carcinoma.
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Authors
Vítor Trovisco, Paula Soares, Manuel Sobrinho-Simões,