| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4136407 | Pathologie Biologie | 2011 | 4 Pages |
Abstract
Merkel cell carcinoma (MCC) is a neuroendocrine carcinoma of the skin of poor outcome. A new type of virus, isolated in 2008, was found to be strongly associated with CCM. This virus, belonging to the family of polyomavirus, was called MCPyV for Merkel Carcinoma Polyomavirus. Recent data favour a causative role of MCPyV in oncogenesis. MCC represents thus a new model for the understanding of the mechanisms of oncogenesis. The distinct molecular viral signature in every case of MCC represents an original tool for the follow-up of the disease. New therapeutic perspectives are to be drawn using this model.
Related Topics
Health Sciences
Medicine and Dentistry
Pathology and Medical Technology
Authors
X. Sastre-Garau,