Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4136986 | Pathophysiology | 2014 | 11 Pages |
Abstract
The history of autoimmune thyroiditis (AIT) and its role in pathophysiology of transition from adolescent hypothalamic syndrome (obesity with rose striae) into early metabolic syndrome is reviewed. Marfanoid phenotype and chronic disequilibrium between local, autacoid-mediated and systemic, hormone-mediated regulation, typical for inherited connective tissue disorders, may promote this transition. Pathogenetic roles of hyperprolactinemia and cytokine misbalance are evaluated and discussed in its pathogenesis.
Keywords
Related Topics
Health Sciences
Medicine and Dentistry
Pathology and Medical Technology
Authors
L.P. Churilov, Yu.I. Stroev, I.Yu. Serdyuk, O.M. Kaminova-Mudzhikova, I.V. Belyaeva, A.N. Gvozdetsky, N.A. Nitsa, L.R. Mikhailova,