Factores histopatológicos con valor pronóstico en el cordoma sacro. Estudio de 10 casos del Hospital Universitario Doctor Peset y el Hospital Clínico Universitario de Valencia

Chordomas are rare midline neoplasms arising from notochord tissue remnants. They account for 1-4% of all bone malignancies. Although considered to be slow growing, low grade neoplasms which rarely metastasize, their tendency for local invasion and frequent recurrence mean that they have a considerable late mortality rate. Several clinical and biological factors have been proposed as prognostic indicators, however, histopathological characteristics have not yet been considered. Our aim is to evaluate the histopathological features of ten cases of chordoma in relation to the clinical outcome.