Carcinoma de mama con células gigantes tipo osteoclasto. Informe de un caso de una variante rara

Breast carcinoma with osteoclast-like giant cells (BCOGC) is a rare, distinctive form of breast cancer. Although cases have been reported with many growth patterns in almost all types of breast cancer, being rarely found in well differentiated tumours. We report a case of well-differentiated ductal carcinoma with abundant osteoclast-like giant cells (OGC). Immunohistochemistry demonstrated the immunophenotypic differences of the tumour and the OGC. The literature is reviewed, illustrating the characteristic morphology and the differential diagnosis is discussed.