Reacciones cutáneas a tratamientos farmacológicos y cosméticos

At the present time, one of the leading causes of biopsy among non-tumoral dermatological diseases is skin reaction to cosmetics or drugs. Due to the continuous advent of new pharmacological treatments and the appearance of novel cosmetic procedures, pathologists must be prepared to recognize their cutaneous adverse reactions. These reactions can adopt practically every histopathological pattern and even trigger the appearance of a dermatosis in a predisposed individual. As in most other dermatological diseases, the diagnosis of cutaneous adverse drug reactions is based on clinico-pathological correlation. Nevertheless, there are some histopathological clues that can suggest this diagnosis such as the presence of eosinophilia and/or dyskeratosis and the combination of unusual and apparently incongruent histopathological patterns.