Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4147051 | Archives de Pédiatrie | 2011 | 4 Pages |
Abstract
We describe 3 cases of chronic purpuric skin lesions in children suffering from systemic vasculitis: 3 children with Henoch-Schönlein purpura. Dapsone was introduced when skin lesions were recurrent, extensive, and persistent, due to its known ability to act as an anti-IgA and as an anticytotoxic agent against polynuclear neutrophils. Fast and complete but purely suspensive healing of skin lesions was noted. One child developed methemoglobinemia, a known side-effect of dapsone, highlighting the need for adequate prescription and follow-up.
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Authors
N. Mazille, D. Lipsker, M. Fischbach,