Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4147859 | Archives de Pédiatrie | 2011 | 6 Pages |
Abstract
Studies on probiotics had found a benefit in their use. That was attributed to a barrier effect at the intestinal mucosa. We tried a new immunephysiological explanation supported by murine works and in humans. Immune modulation by probiotic bacteria and induce IL10 producing regulatory T cells. Receptors DCSIGN and Toll dendrites cells interfere in the copresentation of antigens and generate an immune response modulation by regulatory T cells and their inhibitory cytokines TGFβ, IL10.
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Authors
J.-P. Magny,