Thoracic spinal meningioma in a child with Down syndrome: A case report and review of the literature

Down syndrome is the most common genetic chromosomal disorder and occurs in one out of every 700 newborns. It is well-established that individuals with Down syndrome exhibit a unique tumor profile. These individuals are predisposed to certain neoplasms, such as leukemia and other hematological malignancies. However, solid tumors are exceptionally rare. Central nervous system (CNS) tumors in individuals with Down syndrome have been reported in only a small number of case reports. The majority of these tumors are gliomas and germ cell tumors. Meningiomas have yet to be reported in Down syndrome. We report the first case of a meningioma tumor in an individual with Down syndrome. We present a case of spinal meningioma in a 14-year-old boy with Down syndrome.