Article ID Journal Published Year Pages File Type
4155086 Journal of Pediatric Surgery 2015 5 Pages PDF
Abstract

AimFundoplication has high failure rates in neurodisability: esophagogastric dissociation (TOGD) has been proposed as an alternative. This study aimed to compare the long-term and ‘patient-reported’ outcomes of TOGD and laparoscopic fundoplication (LapFundo).MethodsMatched cohort comparison comprises (i) retrospective analysis from a prospective database and (ii) carer questionnaire survey of symptoms and quality of life (CP-QoL-Child). Children were included if they had severe neurodisability (Gross Motor Function Classification System five) and spasticity.ResultsGroups were similar in terms of previous surgery and comorbidities. The TOGD group was younger (22 vs. 31.5 months, p = 0.038) with more females (18/23 vs. 11/24, p = 0.036). TOGD was more likely to require intensive care: operative time, length of stay and time to full feeds were all longer (p < 0.0001). Median follow-up was 6.3 and 5.8 years. Rates of complications were comparable. Symptom recurrence (5/24 vs. 1/23, p = 0.34) and use of acid-reducing medication (13/24 vs. 4/23, p = 0.035) were higher for LapFundo. Carer-reported symptoms and QoL were similar.ConclusionsTOGD had similar efficacy to LapFundo (with suggestion of lower failure), with comparable morbidity and carer-reported outcomes. However, TOGD was more ‘invasive,’ requiring longer periods of rehabilitation. Families should be offered both procedures as part of comprehensive preoperative counseling.

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Health Sciences Medicine and Dentistry Perinatology, Pediatrics and Child Health
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