Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4155496 | Journal of Pediatric Surgery | 2015 | 6 Pages |
Abstract
A combined 35% isopropanol-35% ethanol locking solution inhibits bacterial and fungal growth similarly to 70% ethanol, but results in less precipitate than 70% ethanol when exposed to heparin. Further study of a combined isopropanol-ethanol locking solution for the prevention of catheter-related bloodstream infections should focus on the determination as to whether such a locking solution may reduce the rate of precipitation-related catheter occlusion, and whether it may be administered with low systemic toxicity.
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Authors
Daniel Restrepo, Nicholas S. Laconi, Norma A. Alcantar, Leigh A. West, Audrey L. Buttice, Saumil Patel, Mark L. Kayton,