Article ID Journal Published Year Pages File Type
4160007 Journal of Pediatric Surgery 2007 6 Pages PDF
Abstract
This study demonstrates reduced expression of Shh and its target genes in ARMs in ETU-exposed fetal rats. Neurons in the myenteric plexus were decreased in high and low types of ARMs. Our results support a role for the Shh cascade during development of the ENS during hindgut development.
Keywords
Related Topics
Health Sciences Medicine and Dentistry Perinatology, Pediatrics and Child Health
Preview
The contribution of the sonic hedgehog cascade in the development of the enteric nervous system in fetal rats with anorectal malformations
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