| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4160234 | Journal of Pediatric Surgery | 2006 | 9 Pages |
Abstract
Inhibition of the PI3K/Akt pathway does not increase the sensitivity of neuroblastoma cell lines to TRAIL-induced apoptosis. Neuroblastoma is unique in that activation of the PI3K/Akt pathway is either not essential to its TRAIL resistance or counteracted because of the multiple repetitive pathways of TRAIL resistance.
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Authors
Philip A. Efron, Mike K. Chen, Meera Iyengar, Wei Dai, Abhilasha Nagaram, Elizabeth A. Beierle,