Article ID Journal Published Year Pages File Type
4160811 Journal of Pediatric Surgery 2006 6 Pages PDF
Abstract
Although in vitro coculture with NB does not induce significant changes in either CCR7 or CCL19 expression, profound functional impairments in CCR7/CCL19-mediated migration occurs. These findings suggest that intracellular signal transduction pathways for these chemokines may be impaired by tumor. Targeting this chemokine-receptor pathway may provide a novel therapeutic strategy.
Related Topics
Health Sciences Medicine and Dentistry Perinatology, Pediatrics and Child Health
Authors
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