Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4162029 | Journal of Pediatric Urology | 2015 | 5 Pages |
Abstract
We assessed the impact of the genetic variability of the AXIN1 gene on cryptorchidism. We have offered primary evidence that the T allele and T/T genotype of rs370681 polymorphisms and C/T genotype of rs1805105 polymorphisms in AXIN1 gene are more frequent in patients with cryptorchidism.Table. Three tag SNPs in AXIN1 gene and cryptorchidism risk.Tag SNPGenetic modelDominantRecessiveOverdominantOR (95% CI)pOR (95% CI)P-valueOR (95% CI)prs3706812.44 (1.47-4.00)4eâ042.56 (1.22-5.26)0.0121.54 (0.96-2.50)0.074rs18051051.64 (1.02-2.63)0.0411.01 (0.44-2.31)0.981.72 (1.05-2.86)0.032rs129218621.44 (0.67-3.06)0.343.22 (0.37-27.91)0.231.22 (0.55-2.74)0.62Note. Values in bold indicate a significant difference at the 5% level. ORÂ =Â odds ration; SNPÂ =Â single nucleotide polymorphism.
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Authors
Bin Zhou, Tielong Tang, Peng Chen, Yan Pu, Mingfu Ma, Danyan Zhang, Lianbing Li, Peng Zhang, Yaping Song, Lin Zhang,