| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4164389 | The Journal of Pediatrics | 2016 | 11 Pages |
Abstract
This study presents comprehensive, unrestricted profiles of the TRB/IGH-CDR3 repertoire of newborns, pregnant women, and healthy adults at a sequence-level resolution. Our data may contribute to a better understanding of the immune system of newborns and benefit the efficient application of umbilical cord blood transplantation in future.
Keywords
N additionCDR3UCBIgHNGSd50PBMCHSCTRBinterleukinHighNext-generation sequencingDiversityHigh-throughput sequencingUmbilical cord bloodImmunoglobulin heavy chainHematopoietic stem cellPeripheral blood mononuclear cellDiversity indexVariablebone marrowcomplementarity determining region 3Nucleotidespolymerase chain reactionPCRJoining
Related Topics
Health Sciences
Medicine and Dentistry
Perinatology, Pediatrics and Child Health
Authors
Changlong MD, PhD, Qidi MD, PhD, Xiaofang MD, Ying MD, PhD, Xin PhD, Lisha MD, Ruikun PhD, Meng MD, Guangyu MD, Yue MD, Zuoqi MD, Jian MD, PhD, Shuhua PhD, Xuerui MD, PhD, Li MD, Song MD, Huiying MD, Chunlin PhD, Xu MD, PhD,